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MOVER · MON OCT 12 2026

Why SNDX fell 24.8% on Oct 12 2026: phase 2 trial failure

SNDX-24.8%on Mon Oct 12 2026

Syndax Pharmaceuticals, Inc. was down 24.8% on the day at $12.78, ranked #10 on 1.4× its usual five-minute volume, when TapeRank recorded this drop at 16:02 ET during after hours.

THE DAY ON THE LIST · 1 EVENT

  1. 16:02 ET
    MOVER · AFTER-HOURS

    $12.78 · ▼ 24.8% ON THE DAY · 1.4× 5M RVOL · RANK #10

    JUSTIFIEDCONFIDENCE5/5

    SNDX fell 41.1% to $10.00, including a 39.61% drop in the last five minutes. The Phase 2 axatilimab trial missed its primary endpoint and IPF development was halted, a major clinical setback that supports the sharp decline.

    WHYA 41% one-day plunge and near-40% late-session collapse are large but proportionate to a failed Phase 2 endpoint and termination of the IPF program.
    ANALYZED 16:02 ET · <1 MIN AGO · OPENAI/GPT-5.6-LUNA
    THE ROW AND SESSION LEVELS AT 16:02 ET
    LAST12.78
    DAY▼ 24.8%
    5 MIN▼ 22.83%
    5M RVOL1.4×
    5M $VOL$2.0M
    FLOAT*88.6M
    RANK#10
    SESSIONAFTER-HOURS
    VWAP16.43
    HOD17.03
    LOD9.00
    OR HIGH16.89
    OR LOW16.76
    PREV CLOSE16.99
    PM HIGH17.03
    PM LOW16.95
    GAP▼ 0.65%

    * FLOAT IS SHARES OUTSTANDING; TRUE FREE FLOAT IS NOT AVAILABLE

THE SESSION

  • 09:30 ETOpened at $16.88, -0.7% on the previous close of $16.99
  • 09:36 ETRegular-session high, $16.95
  • 15:11 ETRegular-session low, $16.37
  • 15:59 ETLast trade of the regular session, $16.54, -2.6% on the previous close of $16.99
  • Volume: 989K shares in regular hours, 601 before the open

SNDX opened at $16.88, briefly reached $16.95, and then declined to a $16.37 low before ending the regular session at $16.54, down 2.6% from the previous close. There were no halts, but TapeRank later recorded a sharp move to $12.78 at 16:02 ET; its read tied the decline to Syndax’s announcement that the Phase 2 axatilimab trial in idiopathic pulmonary fibrosis missed its primary endpoint and that IPF development was halted, calling the move justified with 5/5 confidence.

WRITTEN THU OCT 15 2026 18:04 ET BY OPENAI/GPT-5.6-LUNA FROM THE FACTS ON THIS PAGE

FILINGS AND NEWS · 24H BEFORE THE MOVE

On the tape right now

WHERE THE LIST STOODWED NOV 4 2026 · 13:49 ETRECORDED LIVE · 742 QUALIFY

01
ECGSURGING 0:05
79.71
▼ 29.3%
▼ 1.41%
41.0×
FAD
$6.2M
51.1M*
STRETCHED
02
CAVASURGING 0:00
64.78
▲ 7.4%
▲ 1.30%
9.3×
ORBHODVWH
$11.6M
116.8M*
UNEXPLAINED
03
URGNSURGING 0:00
29.16
▼ 15.2%
▼ 1.29%
15.6×
FAD
$1.4M
48.9M*
JUSTIFIED
04
MPTISURGING 0:00
64.15
▼ 1.5%
▲ 0.96%
23.8×
VWH
$637K
4.3M*
UNEXPLAINED
05
LSPDSURGING 0:00
11.52
▲ 4.9%
▼ 1.24%
16.5×
ORB
$426K
133.3M*
UNEXPLAINED
06
CRCTSURGING 0:00
8.90
▲ 49.2%
▼ 0.72%
15.1×
GAPORBVWHEXT
$395K
54.7M*
STRETCHED
07
BROSSURGING 0:00
43.97
▲ 0.9%
▼ 0.91%
4.0×
FAD
$4.3M
137.9M*
UNEXPLAINED
08
LMRICOOLING 1:35
12.85
▲ 14.5%
▲ 1.06%
132×
ORBHODVWH
$1.7M
—
UNEXPLAINED
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