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MOVER · FRI OCT 16 2026

Why GUTS fell 26.2% on Oct 16 2026: positive pivotal data

GUTS-26.2%on Fri Oct 16 2026

Fractyl Health, Inc. Common Stock was down 26.2% on the day at $3.07, ranked #2 on 1778× its usual five-minute volume, when TapeRank recorded this drop at 07:21 ET during the pre-market session.

THE DAY ON THE LIST · 1 EVENT

  1. 07:21 ET
    MOVER · PRE-MARKET

    $3.07 · ▼ 26.2% ON THE DAY · 1778× 5M RVOL · RANK #2

    JUSTIFIEDCONFIDENCE5/5

    Fractyl Health reported positive six-month REMAIN-1 pivotal data showing significantly better weight-loss retention than sham, alongside Breakthrough Device status and a planned FDA submission. The stock is up 7.8% pre-market on a concrete clinical milestone with quantified efficacy, making the move proportionate to the news.

    WHYUp 7.8% on statistically significant pivotal-study results showing 80% versus 67% weight-loss retention is a meaningful but not excessive reaction to the catalyst.
    ANALYZED 07:06 ET · 15 MIN AGO · OPENAI/GPT-5.6-LUNA
    THE ROW AND SESSION LEVELS AT 07:21 ET
    LAST3.07
    DAY▼ 26.2%
    5 MIN▼ 34.41%
    5M RVOL1778×
    5M $VOL$4.0M
    FLOAT*159.2M
    RANK#2
    SESSIONPRE-MARKET
    VWAP4.42
    HOD4.84
    LOD3.32
    OR HIGH—
    OR LOW—
    PREV CLOSE4.16
    PM HIGH4.84
    PM LOW3.32
    GAP▼ 14.66% (indicated)

    * FLOAT IS SHARES OUTSTANDING; TRUE FREE FLOAT IS NOT AVAILABLE

    — MEANS THE LEVEL DID NOT EXIST YET AT THAT INSTANT, NOT ZERO

THE SESSION

  • 09:30 ETOpened at $2.14, -48.6% on the previous close of $4.16
  • 10:16 ETRegular-session high, $2.30
  • 15:51 ETRegular-session low, $1.53
  • 15:59 ETLast trade of the regular session, $1.55, -62.6% on the previous close of $4.16
  • Volume: 6.4M shares in regular hours, 8.3M before the open

GUTS opened at $2.14 after TapeRank read its premarket move as tied to Fractyl Health’s positive REMAIN-1 pivotal data, which showed 80% retention of GLP-1-induced weight loss versus 67% for sham, along with Breakthrough Device status and a planned FDA submission. It briefly reached $2.30 before reversing through the session to a $1.53 low and finishing at $1.55, down 62.6% from the previous close; TapeRank recorded no halts.

WRITTEN FRI OCT 16 2026 16:00 ET BY OPENAI/GPT-5.6-LUNA FROM THE FACTS ON THIS PAGE

FILINGS AND NEWS · 24H BEFORE THE MOVE

On the tape right now

WHERE THE LIST STOODWED NOV 4 2026 · 13:49 ETRECORDED LIVE · 742 QUALIFY

01
ECGSURGING 0:05
79.71
▼ 29.3%
▼ 1.41%
41.0×
FAD
$6.2M
51.1M*
STRETCHED
02
CAVASURGING 0:00
64.78
▲ 7.4%
▲ 1.30%
9.3×
ORBHODVWH
$11.6M
116.8M*
UNEXPLAINED
03
URGNSURGING 0:00
29.16
▼ 15.2%
▼ 1.29%
15.6×
FAD
$1.4M
48.9M*
JUSTIFIED
04
MPTISURGING 0:00
64.15
▼ 1.5%
▲ 0.96%
23.8×
VWH
$637K
4.3M*
UNEXPLAINED
05
LSPDSURGING 0:00
11.52
▲ 4.9%
▼ 1.24%
16.5×
ORB
$426K
133.3M*
UNEXPLAINED
06
CRCTSURGING 0:00
8.90
▲ 49.2%
▼ 0.72%
15.1×
GAPORBVWHEXT
$395K
54.7M*
STRETCHED
07
BROSSURGING 0:00
43.97
▲ 0.9%
▼ 0.91%
4.0×
FAD
$4.3M
137.9M*
UNEXPLAINED
08
LMRICOOLING 1:35
12.85
▲ 14.5%
▲ 1.06%
132×
ORBHODVWH
$1.7M
—
UNEXPLAINED
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