MOVER · TUE SEP 8 2026

Why PHVS rose 26.7% on Sep 8 2026: positive pivotal trial data

PHVS+26.7%on Tue Sep 8 2026

Pharvaris N.V. Ordinary Shares was up 26.7% on the day at $44.66, ranked #2 on 90.5× its usual five-minute volume, when TapeRank recorded this spike at 07:16 ET during the pre-market session.

THE DAY ON THE LIST · 1 EVENT

  1. 07:16 ET
    MOVER · PRE-MARKET

    $44.66 · ▲ 26.7% ON THE DAY · 90.5× 5M RVOL · RANK #2

    JUSTIFIEDCONFIDENCE5/5

    Pharvaris shares are up roughly 25% pre-market after announcing positive topline data from the CHAPTER-3 pivotal study of deucrictibant XR for HAE attack prophylaxis, a binding, quantifiable clinical readout rather than a vague partnership. The pullback in the last five minutes reflects normal profit-taking and volatility after the initial pop on heavy volume.

    WHYA positive pivotal phase 3 readout is a major binary catalyst for a clinical-stage biotech, and a 25% move is proportionate to de-risking a lead pipeline asset ahead of potential regulatory filing.
    ANALYZED 07:17 ET · <1 MIN AGO · ANTHROPIC/CLAUDE-SONNET-5
    THE ROW AND SESSION LEVELS AT 07:16 ET
    LAST44.66
    DAY▲ 26.7%
    5 MIN▼ 2.04%
    5M RVOL90.5×
    5M $VOL$1.4M
    FLOAT*65.4M
    RANK#2
    SESSIONPRE-MARKET
    VWAP43.44
    HOD48.00
    LOD36.95
    OR HIGH—
    OR LOW—
    PREV CLOSE35.25
    PM HIGH48.00
    PM LOW36.95
    GAP▲ 29.79% (indicated)

    * FLOAT IS SHARES OUTSTANDING; TRUE FREE FLOAT IS NOT AVAILABLE

    — MEANS THE LEVEL DID NOT EXIST YET AT THAT INSTANT, NOT ZERO

THE SESSION

  • 09:30 ETOpened at $40.96, +16.2% on the previous close of $35.25
  • 09:33 ETRegular-session high, $43.25
  • 13:37 ETRegular-session low, $37.60
  • 15:59 ETLast trade of the regular session, $37.75, +7.1% on the previous close of $35.25
  • Volume: 5.5M shares in regular hours, 619K before the open

PHVS was already running premarket, up about 27% near $44.66 by 07:16 ET, with TapeRank tying the move to positive pivotal CHAPTER-3 trial data for deucrictibant XR in HAE attack prophylaxis, a binding clinical readout it judged fully justified at the highest confidence. Shares opened the regular session up 16.2% at $40.96, spiked to $43.25 by 09:33 ET, then faded through the day to a low of $37.60 at 13:37 ET on heavy volume. The stock closed the session at $37.75, finishing up 7.1% from the prior close with no halts recorded.

WRITTEN THU OCT 15 2026 17:42 ET BY ANTHROPIC/CLAUDE-SONNET-5 FROM THE FACTS ON THIS PAGE

FILINGS · 24H BEFORE THE MOVE

On the tape right now

WHERE THE LIST STOODWED NOV 4 2026 · 13:49 ETRECORDED LIVE · 742 QUALIFY

01
ECGSURGING 0:05
79.71
▼ 29.3%
▼ 1.41%
41.0×
FAD
$6.2M
51.1M*
STRETCHED
02
CAVASURGING 0:00
64.78
▲ 7.4%
▲ 1.30%
9.3×
ORBHODVWH
$11.6M
116.8M*
UNEXPLAINED
03
URGNSURGING 0:00
29.16
▼ 15.2%
▼ 1.29%
15.6×
FAD
$1.4M
48.9M*
JUSTIFIED
04
MPTISURGING 0:00
64.15
▼ 1.5%
▲ 0.96%
23.8×
VWH
$637K
4.3M*
UNEXPLAINED
05
LSPDSURGING 0:00
11.52
▲ 4.9%
▼ 1.24%
16.5×
ORB
$426K
133.3M*
UNEXPLAINED
06
CRCTSURGING 0:00
8.90
▲ 49.2%
▼ 0.72%
15.1×
GAPORBVWHEXT
$395K
54.7M*
STRETCHED
07
BROSSURGING 0:00
43.97
▲ 0.9%
▼ 0.91%
4.0×
FAD
$4.3M
137.9M*
UNEXPLAINED
08
LMRICOOLING 1:35
12.85
▲ 14.5%
▲ 1.06%
132×
ORBHODVWH
$1.7M
—
UNEXPLAINED
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