UNEXPLAINED MOVE · MOVER · THU OCT 29 2026

Why IOVA fell 20.1% on Oct 29 2026: phase 2 data update

IOVA-20.1%on Thu Oct 29 2026

Iovance Biotherapeutics, Inc. Common Stock was down 20.1% on the day at $11.83, ranked #5 on 179× its usual five-minute volume, when TapeRank recorded this drop at 07:46 ET during the pre-market session. TapeRank recorded 2 events for IOVA that day, between 04:32 and 07:46 ET, and each is in the timeline below.

THE DAY ON THE LIST · 2 EVENTS

  1. 04:32 ET
    UNEXPLAINED MOVE · PRE-MARKET

    $17.25 · ▲ 16.5% ON THE DAY · 5.4× 5M RVOL · RANK #1

    UNEXPLAINEDNO FILINGS · RULE

    IOVA is up 11.3% on the day on 4.3x its normal volume for this time of day. No filings or headlines were found in SEC EDGAR filings and Benzinga wire headlines in the last 24 hours, so this is order flow rather than a disclosed catalyst.

    WHYNo filings or headlines within 24 hours of the move.
    ANALYZED 04:19 ET · 13 MIN AGO · RULE, NO MODEL
    THE ROW AND SESSION LEVELS AT 04:32 ET
    LAST17.25
    DAY▲ 16.5%
    5 MIN▲ 3.48%
    5M RVOL5.4×
    5M $VOL$124K
    FLOAT*453.0M
    RANK#1
    SESSIONPRE-MARKET
    VWAP16.57
    HOD17.06
    LOD16.31
    OR HIGH—
    OR LOW—
    PREV CLOSE14.81
    PM HIGH17.06
    PM LOW16.31
    GAP▲ 13.44% (indicated)

    * FLOAT IS SHARES OUTSTANDING; TRUE FREE FLOAT IS NOT AVAILABLE

    — MEANS THE LEVEL DID NOT EXIST YET AT THAT INSTANT, NOT ZERO

  2. 07:46 ET
    MOVER · PRE-MARKET

    $11.83 · ▼ 20.1% ON THE DAY · 179× 5M RVOL · RANK #5

    STRETCHEDCONFIDENCE4/5

    Iovance is down 11.9% pre-market after updated Phase 2 lung-cancer data showed a 24.6% objective response rate, consistent with previously reported results. The planned 2027 supplemental filing and future biomarker-enriched study are incremental, so the sharp selloff is larger than this largely reaffirming update supports.

    WHYA 11.9% decline is outsized relative to data that were consistent with prior results and included only a planned 2027 filing and future study.
    ANALYZED 07:42 ET · 3 MIN AGO · OPENAI/GPT-5.6-LUNA
    THE ROW AND SESSION LEVELS AT 07:46 ET
    LAST11.83
    DAY▼ 20.1%
    5 MIN▼ 8.79%
    5M RVOL179×
    5M $VOL$3.8M
    FLOAT*453.0M
    RANK#5
    SESSIONPRE-MARKET
    VWAP13.90
    HOD17.25
    LOD11.91
    OR HIGH—
    OR LOW—
    PREV CLOSE14.81
    PM HIGH17.25
    PM LOW11.91
    GAP▼ 19.31% (indicated)

    * FLOAT IS SHARES OUTSTANDING; TRUE FREE FLOAT IS NOT AVAILABLE

    — MEANS THE LEVEL DID NOT EXIST YET AT THAT INSTANT, NOT ZERO

THE SESSION

  • 09:30 ETOpened at $10.70, -27.8% on the previous close of $14.81
  • 09:37 ETRegular-session high, $11.58
  • 11:10 ETRegular-session low, $9.35
  • 15:59 ETLast trade of the regular session, $9.55, -35.5% on the previous close of $14.81
  • Volume: 46.1M shares in regular hours, 10.7M before the open

IOVA opened at $10.70, briefly reached $11.58, then fell to $9.35 by 11:10 ET before ending the regular session at $9.55, down 35.5% from the previous close. TapeRank tied the premarket selloff to Iovance’s updated Phase 2 lung-cancer data, which showed a 24.6% objective response rate consistent with previously reported results, along with a planned 2027 filing and future study; it judged the decline stretched relative to that update. TapeRank also recorded an earlier unexplained move because no filings or headlines within 24 hours explained it, and no halts occurred.

WRITTEN THU OCT 29 2026 16:00 ET BY OPENAI/GPT-5.6-LUNA FROM THE FACTS ON THIS PAGE

FILINGS AND NEWS · 24H BEFORE THE MOVE

On the tape right now

WHERE THE LIST STOODWED NOV 4 2026 · 13:49 ETRECORDED LIVE · 742 QUALIFY

01
ECGSURGING 0:05
79.71
▼ 29.3%
▼ 1.41%
41.0×
FAD
$6.2M
51.1M*
STRETCHED
02
CAVASURGING 0:00
64.78
▲ 7.4%
▲ 1.30%
9.3×
ORBHODVWH
$11.6M
116.8M*
UNEXPLAINED
03
URGNSURGING 0:00
29.16
▼ 15.2%
▼ 1.29%
15.6×
FAD
$1.4M
48.9M*
JUSTIFIED
04
MPTISURGING 0:00
64.15
▼ 1.5%
▲ 0.96%
23.8×
VWH
$637K
4.3M*
UNEXPLAINED
05
LSPDSURGING 0:00
11.52
▲ 4.9%
▼ 1.24%
16.5×
ORB
$426K
133.3M*
UNEXPLAINED
06
CRCTSURGING 0:00
8.90
▲ 49.2%
▼ 0.72%
15.1×
GAPORBVWHEXT
$395K
54.7M*
STRETCHED
07
BROSSURGING 0:00
43.97
▲ 0.9%
▼ 0.91%
4.0×
FAD
$4.3M
137.9M*
UNEXPLAINED
08
LMRICOOLING 1:35
12.85
▲ 14.5%
▲ 1.06%
132×
ORBHODVWH
$1.7M
—
UNEXPLAINED
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