UNEXPLAINED MOVE · MOVER · TUE SEP 22 2026

Why CLDX fell 21.1% on Sep 22 2026: phase 3 trial results

CLDX-21.1%on Tue Sep 22 2026

Celldex Therapeutics, Inc was down 21.1% on the day at $29.90, ranked #1 on 281× its usual five-minute volume, when TapeRank recorded this drop at 08:04 ET during the pre-market session. TapeRank recorded 2 events for CLDX that day, between 06:59 and 08:04 ET, and each is in the timeline below.

THE DAY ON THE LIST · 2 EVENTS

  1. 06:59 ET
    UNEXPLAINED MOVE · PRE-MARKET

    $43.78 · ▲ 15.5% ON THE DAY · 18.0× 5M RVOL · RANK #2

    UNEXPLAINEDNO FILINGS · RULE

    CLDX is up 2.8% on the day on 17.6x its normal volume for this time of day. No filings or headlines were found in SEC EDGAR filings and Benzinga wire headlines in the last 24 hours, so this is order flow rather than a disclosed catalyst.

    WHYNo filings or headlines within 24 hours of the move.
    ANALYZED 06:59 ET · <1 MIN AGO · RULE, NO MODEL
    THE ROW AND SESSION LEVELS AT 06:59 ET
    LAST43.78
    DAY▲ 15.5%
    5 MIN▲ 13.83%
    5M RVOL18.0×
    5M $VOL$123K
    FLOAT*78.5M
    RANK#2
    SESSIONPRE-MARKET
    VWAP39.40
    HOD38.95
    LOD38.21
    OR HIGH—
    OR LOW—
    PREV CLOSE37.89
    PM HIGH38.95
    PM LOW38.21
    GAP▲ 2.80% (indicated)

    * FLOAT IS SHARES OUTSTANDING; TRUE FREE FLOAT IS NOT AVAILABLE

    — MEANS THE LEVEL DID NOT EXIST YET AT THAT INSTANT, NOT ZERO

  2. 08:04 ET
    MOVER · PRE-MARKET

    $29.90 · ▼ 21.1% ON THE DAY · 281× 5M RVOL · RANK #1

    JUSTIFIEDCONFIDENCE4/5

    Celldex is down 6.3% pre-market, with a further 4.08% drop in five minutes, despite reporting positive Phase 3 results for barzolvolimab. The news is materially favorable, so the selloff appears driven by market reaction or positioning rather than a negative trial outcome.

    WHYA 6.3% decline is modest relative to the significance of two successful Phase 3 trials, making the move proportionate as a market repricing rather than an outsized reaction.
    ANALYZED 07:35 ET · 28 MIN AGO · OPENAI/GPT-5.6-LUNA
    THE ROW AND SESSION LEVELS AT 08:04 ET
    LAST29.90
    DAY▼ 21.1%
    5 MIN▼ 12.60%
    5M RVOL281×
    5M $VOL$4.6M
    FLOAT*78.5M
    RANK#1
    SESSIONPRE-MARKET
    VWAP40.61
    HOD53.65
    LOD32.42
    OR HIGH—
    OR LOW—
    PREV CLOSE37.89
    PM HIGH53.65
    PM LOW32.42
    GAP▼ 14.43% (indicated)

    * FLOAT IS SHARES OUTSTANDING; TRUE FREE FLOAT IS NOT AVAILABLE

    — MEANS THE LEVEL DID NOT EXIST YET AT THAT INSTANT, NOT ZERO

THE SESSION

  • 09:30 ETOpened at $36.60, -3.4% on the previous close of $37.89
  • 09:44 ETRegular-session high, $38.39
  • 10:36 ETRegular-session low, $30.39
  • 15:59 ETLast trade of the regular session, $33.53, -11.5% on the previous close of $37.89
  • Volume: 10.6M shares in regular hours, 2.1M before the open

CLDX began with an unexplained premarket move, reaching $43.78 at 06:59 ET before falling to $29.90 by 08:04 ET, its largest recorded move at -21.1%. TapeRank tied the move to Celldex’s report of positive Phase 3 results for barzolvolimab in chronic spontaneous urticaria, while noting that the selloff followed favorable trial news and was a market repricing rather than a negative outcome; it also found no filings or headlines explaining the move under its rule. The stock opened at $36.60, rose to $38.39, dropped to a $30.39 low, and finished at $33.53, down 11.5% from the previous close, with no halts.

WRITTEN THU OCT 15 2026 17:53 ET BY OPENAI/GPT-5.6-LUNA FROM THE FACTS ON THIS PAGE

FILINGS AND NEWS · 24H BEFORE THE MOVE

On the tape right now

WHERE THE LIST STOODWED NOV 4 2026 · 13:49 ETRECORDED LIVE · 742 QUALIFY

01
ECGSURGING 0:05
79.71
▼ 29.3%
▼ 1.41%
41.0×
FAD
$6.2M
51.1M*
STRETCHED
02
CAVASURGING 0:00
64.78
▲ 7.4%
▲ 1.30%
9.3×
ORBHODVWH
$11.6M
116.8M*
UNEXPLAINED
03
URGNSURGING 0:00
29.16
▼ 15.2%
▼ 1.29%
15.6×
FAD
$1.4M
48.9M*
JUSTIFIED
04
MPTISURGING 0:00
64.15
▼ 1.5%
▲ 0.96%
23.8×
VWH
$637K
4.3M*
UNEXPLAINED
05
LSPDSURGING 0:00
11.52
▲ 4.9%
▼ 1.24%
16.5×
ORB
$426K
133.3M*
UNEXPLAINED
06
CRCTSURGING 0:00
8.90
▲ 49.2%
▼ 0.72%
15.1×
GAPORBVWHEXT
$395K
54.7M*
STRETCHED
07
BROSSURGING 0:00
43.97
▲ 0.9%
▼ 0.91%
4.0×
FAD
$4.3M
137.9M*
UNEXPLAINED
08
LMRICOOLING 1:35
12.85
▲ 14.5%
▲ 1.06%
132×
ORBHODVWH
$1.7M
—
UNEXPLAINED
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