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MOVER · WED NOV 4 2026

Why CGEM fell 20.2% on Nov 4 2026: phase 1 data

CGEM-20.2%on Wed Nov 4 2026

Cullinan Therapeutics, Inc. Common Stock was down 20.2% on the day at $12.57, ranked #8 on 14.6× its usual five-minute volume, when TapeRank recorded this drop at 13:08 ET during regular hours.

THE DAY ON THE LIST · 1 EVENT

  1. 13:08 ET
    MOVER · REGULAR

    $12.57 · ▼ 20.2% ON THE DAY · 14.6× 5M RVOL · RANK #8

    STRETCHEDCONFIDENCE4/5

    CGEM is down 20.1% after updated Phase 1 CLN-049 data showed meaningful CRS and other adverse events, despite mitigation with two-step dosing. The clinical update is concrete but does not explain a one-fifth decline on its face, making the move substantially larger than the disclosed news.

    WHYDown 20.1% on Phase 1 safety data with partial toxicity mitigation is a much larger move than the quantified update alone supports.
    ANALYZED 13:37 ET · <1 MIN AGO · OPENAI/GPT-5.6-LUNA
    THE ROW AND SESSION LEVELS AT 13:08 ET
    LAST12.57
    DAY▼ 20.2%
    5 MIN▼ 4.16%
    5M RVOL14.6×
    5M $VOL$630K
    FLOAT*64.4M
    RANK#8
    SESSIONREGULAR
    VWAP14.10
    HOD16.29
    LOD12.76
    OR HIGH16.22
    OR LOW15.99
    PREV CLOSE15.75
    PM HIGH16.05
    PM LOW14.75
    GAP▲ 1.52%

    * FLOAT IS SHARES OUTSTANDING; TRUE FREE FLOAT IS NOT AVAILABLE

THE SESSION

  • 09:30 ETOpened at $15.99, +1.5% on the previous close of $15.75
  • 09:35 ETRegular-session high, $16.29
  • 15:03 ETRegular-session low, $11.92
  • 15:59 ETLast trade of the regular session, $12.48, -20.7% on the previous close of $15.75
  • Volume: 1.9M shares in regular hours, 6K before the open

CGEM opened at $15.99 and briefly reached $16.29 before reversing lower through the session, reaching $11.92 at 15:03 ET and ending regular trading at $12.48. TapeRank tied the decline to updated Phase 1 CLN-049 data showing meaningful cytokine release syndrome and other adverse events despite mitigation with two-step dosing, disclosed in a 09:17 ET SEC 8-K; its read was that the clinical update did not explain a decline of this size on its face, rating the move stretched with 4/5 confidence.

WRITTEN WED NOV 4 2026 16:00 ET BY OPENAI/GPT-5.6-LUNA FROM THE FACTS ON THIS PAGE

FILINGS AND NEWS · 24H BEFORE THE MOVE

On the tape right now

WHERE THE LIST STOODWED NOV 4 2026 · 13:49 ETRECORDED LIVE · 742 QUALIFY

01
ECGSURGING 0:05
79.71
▼ 29.3%
▼ 1.41%
41.0×
FAD
$6.2M
51.1M*
STRETCHED
02
CAVASURGING 0:00
64.78
▲ 7.4%
▲ 1.30%
9.3×
ORBHODVWH
$11.6M
116.8M*
UNEXPLAINED
03
URGNSURGING 0:00
29.16
▼ 15.2%
▼ 1.29%
15.6×
FAD
$1.4M
48.9M*
JUSTIFIED
04
MPTISURGING 0:00
64.15
▼ 1.5%
▲ 0.96%
23.8×
VWH
$637K
4.3M*
UNEXPLAINED
05
LSPDSURGING 0:00
11.52
▲ 4.9%
▼ 1.24%
16.5×
ORB
$426K
133.3M*
UNEXPLAINED
06
CRCTSURGING 0:00
8.90
▲ 49.2%
▼ 0.72%
15.1×
GAPORBVWHEXT
$395K
54.7M*
STRETCHED
07
BROSSURGING 0:00
43.97
▲ 0.9%
▼ 0.91%
4.0×
FAD
$4.3M
137.9M*
UNEXPLAINED
08
LMRICOOLING 1:35
12.85
▲ 14.5%
▲ 1.06%
132×
ORBHODVWH
$1.7M
—
UNEXPLAINED
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